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Friday, April 30, 2021

Health Canada holding back 1st batch of J&J COVID-19 vaccines over quality control issues - Global News

Global News previously reported that a substance from the AstraZeneca vaccine was found to be in Johnson & Johnson’s vaccine batch sent to Canada. This has since been corrected to reflect that a substance in the J&J vaccine batch sent to Canada was instead made in the same plant where several millions of other J&J vaccines had spoiled in March.

Health Canada says it will hold back the first batch of 300,000 Johnson & Johnson COVID-19 vaccines after learning that a part of the vaccine was made in the same U.S. plant where millions of doses meant for the U.S. market were spoiled.

According to the agency, a “drug substance” that would then undergo processing to become the final J&J vaccine was made at the Emergent Biosolutions plant in Baltimore, Maryland. The substance was then shipped to a separate site located outside of the U.S. to be created into the final version of the vaccine.

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Read more: Johnson & Johnson vaccine is coming to Canada. How do we use it best?

The U.S. Food and Drug Administration (FDA) previously cited the plant for several violations, including cleaning and sterilization as well as the potential for cross-contamination.

The FDA has since ordered the facility to stop making more J&J vaccines until it addresses the violations and manufacturing errors, which resulted in 15 millions of those doses being destroyed.

In a statement Friday, the health agency said it was working with Janssen and the FDA to assess the vaccines and they would only be released once they were deemed to be safe.

Click to play video: 'White House says Johnson & Johnson remains committed to meeting COVID-19 vaccine contract' White House says Johnson & Johnson remains committed to meeting COVID-19 vaccine contract
White House says Johnson & Johnson remains committed to meeting COVID-19 vaccine contract – Apr 9, 2021

The agency also maintained confidence that the 1.5 million AstraZeneca vaccines also delivered to Canada from that plant in late March were still safe and met “quality specifications.”

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“Since issuing our statement [on AstraZeneca], Health Canada has learned that a drug substance produced at the Emergent site was used in the manufacturing of the initial Janssen vaccines received on April 28 and intended for use in Canada,” read the statement.

Read more: U.S. puts Johnson & Johnson in charge of plant that botched batch of COVID-19 vaccines

“The drug substance is the active ingredient that undergoes further processing before becoming the final product (i.e., the vaccine). The final Janssen vaccines were manufactured at a different site located outside of the U.S.”

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In a tweet Friday, federal Conservative Health Critic Michelle Rempel Garner called Health Canada’s announcement “inexcusable.”

“Why was this communicated at the eleventh hour before shots went into arms?” she wrote.

“We knew these vaccines were coming for weeks. Major screw up with huge implications.”

Health Canada did not add anything further to its statement after being contacted by Global News.

© 2021 Global News, a division of Corus Entertainment Inc.

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Health Canada holding back 1st batch of J&J COVID-19 vaccines over quality control issues - Global News
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Quebec redirects COVID vaccinations from Olympic Stadium because of weekend protest - SooToday

MONTREAL — Quebec is redirecting people from the mass vaccination site at the Olympic Stadium on Saturday because of a planned protest in the area against COVID-19 health orders. 

Health Minister Christian Dubé said Friday on Twitter appointments have been transferred to other clinics in the city. He said the other clinics have the capacity to honour appointments scheduled at the stadium but deplored the fact protesters are choosing to demonstrate outside the mass vaccination site.

The protest is being organized online by a group calling itself Québec Debout (Quebec standing up). It calls the public health orders imposed in the province "excessive and unjustified." Protests are planned in Montreal and several other Quebec cities, according to the group's Facebook page.

Dubé said the government respects the right to demonstrate but vaccination is a priority. "People have a right to their opinion, but I think they could have left those who are getting vaccinated alone," Dubé told TVA network in an interview on Friday.

The regional health authority governing the territory where the stadium is located said it had condensed appointments before 10 a.m. on Saturday and had stopped booking people at that site for the rest of the day in anticipation of the protest.

"The small volume of vaccines available on Saturday combined with the low demand for appointments allowed us to concentrate our meetings in the morning and thus adjust to the context surrounding the event," the health authority said in a statement Friday.

Prime Minister Justin Trudeau told reporters Friday the planned protest is "deeply disappointing." Freedom of speech and assembly are important, especially during a pandemic, but protests must be done safely, he added.

"The irony here is that by gathering, people are putting each other at risk, spreading further cases of COVID-19, and extending the time in which we will have to be faced with restrictions and public health measures,” Trudeau said.

This report by The Canadian Press was first published April 30, 2021.

The Canadian Press

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Quebec redirects COVID vaccinations from Olympic Stadium because of weekend protest - SooToday
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Canada is pausing distribution of Johnson & Johnson vaccines - News 1130

Effective immediately, Canada is pausing distribution of the recent shipment of Johnson & Johnson COVID-19 vaccines.

The recent shipment of the one-dose COVID-19 vaccines from Johnson & Johnson won’t be used, as Health Canada has learned these doses were partially processed in the Baltimore plant that ruined 15 million doses at the beginning of April.

That plant was forced to close, while the United States Food and Drug Administration investigates.

In a statement, Health Canada says those doses will only be released when “once Health Canada is satisfied that they meet the Department’s high standards for quality, safety and efficacy.” Health Canada is currently working with the FDA and Janssen to check these vaccines.

A spokesperson for Health Minister Patty Hajdu says “the government was made aware of this information today – the same day Health Canada decided to communicate it with Canadians.”

The office of Procurement Minister Anita Anand released a statement, which says “an initial shipment of approximately 300,000 doses of the Johnson & Johnson vaccine landed in Canada on Wednesday, April 28. As Health Canada’s review of these vaccines is ongoing, and it works with the supplier to obtain all of the needed information, the government awaits further information prior to their release.”

A Conservative Member of Parliament from Alberta is calling out the Liberal government for the delay on pausing the distribution.

MP Michelle Rempel Garner, of Calgary Nose Hill, says the federal government should’ve released this information earlier “before shots went into arms.”

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Canada is pausing distribution of Johnson & Johnson vaccines - News 1130
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Quebec redirects COVID vaccinations from Olympic Stadium due to weekend protest - q107.com

Quebec is redirecting people from the mass vaccination site at the Olympic Stadium on Saturday because of a planned protest in the area against COVID-19 health orders.

Health Minister Christian Dubé said Friday on Twitter appointments have been transferred to other clinics in the city.

Dubé says the other clinics had the capacity to honour appointments scheduled at the stadium but is deploring the fact protesters are choosing to demonstrate outside the mass vaccination site.

The protest is being organized online by a group calling itself Quebec Debout (Quebec standing up). It calls the public health orders imposed in the province “excessive and unjustified.”

Protests are planned in Montreal and several other Quebec towns, according to the group’s Facebook page.

READ MORE: About 75,000 COVID vaccine appointments booked in Quebec before 10 a.m.

Dubé says the government respects the right to demonstrate but vaccination is a priority.

“People have a right to their opinion, but I think they could have left those who are getting vaccinated alone,” Dube told TVA network in an interview today.

The regional health authority governing the territory where the stadium is located said it had condensed appointments before 10 a.m. on Saturday and had stopped booking people at that site for the rest of the day in anticipation of the protest.

“The small volume of vaccines available on Saturday combined with the low demand for appointments allowed us to concentrate our meetings in the morning and thus adjust to the context surrounding the event,” the health authority said in a statement Friday.

Prime Minister Justin Trudeau told reporters Friday the planned protest is “deeply disappointing.” Freedom of speech and assembly are important, especially during a pandemic, but protests must be done safely, he added.

“The irony here is that by gathering, people are putting each other at risk, spreading further cases of COVID-19, and extending the time in which we will have to be faced with restrictions and public health measures,” Trudeau said.

© 2021 The Canadian Press

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Quebec redirects COVID vaccinations from Olympic Stadium due to weekend protest - q107.com
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Health Canada holding off on Johnson & Johnson COVID-19 vaccine distribution - CBC.ca

Health Canada is holding off on distributing the first shipment of Johnson & Johnson's COVID-19 vaccine after it became clear the doses that arrived on Wednesday were processed in the same U.S. plant that's been mired in quality-control problems.

Reports first surfaced in the New York Times earlier this month about problems at a Baltimore, Md., plant run by Emergent BioSolutions, where both the AstraZeneca-Oxford and Johnson & Johnson vaccines were being manufactured.

Emergent announced earlier this month that 15 million doses of the latter had been ruined by cross-contamination — a development that prompted the White House to put Johnson & Johnson in charge of the facility.

Canada received 300,000 doses this week, Health Canada told CBC News.

Those shots will only be released for distribution once Health Canada ensures they've met its "high standards for quality, safety and efficacy," the federal department said in a statement Friday evening.

Health Canada says it remains "confident" the 1.5 million doses of AstraZeneca vaccine imported from the same facility meet quality specifications.

WATCH | U.S. pauses J&J vaccine over blood clot reports: 

The U.S. investigation of whether six cases of rare blood clots are linked to the Johnson & Johnson COVID-19 vaccine may help give Canada modified guidance on the shot before it reaches Canada, says Dr. Isaac Bogoch, an infectious disease specialist in Toronto. 7:34

The department previously said the J&J doses Canada was expecting were not coming from the Baltimore plant.

"Canadians can be assured that Health Canada is taking all necessary steps to ensure that any products coming from this facility will only be used if they are safe and effective," Health Canada said in a statement on Sunday.

Setback for vaccination efforts

Health Canada's pause on the J&J shot is a setback for the country's efforts to continue ramping up vaccinations amid a raging third wave of the pandemic. 

It also marks the latest hurdle for the single-dose vaccine, which has been long-awaited in hard-hit regions as a way to quickly immunize vulnerable populations

Health Canada approved the vaccine in March, and updated its labelling on Monday to acknowledge the risk of rare but serious blood clots.

The move followed a brief U.S. pause to investigate reports of clots, which have happened in 15 of the roughly 6.8 million Americans who got the shot, according to the U.S. Centers for Disease Control and Prevention.

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Health Canada holding off on Johnson & Johnson COVID-19 vaccine distribution - CBC.ca
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6 Hollyburn Country Club board members resign, less than a week after 'vaccination scandal' - North Shore News

Six members of Hollyburn Country Club’s board of directors have resigned, less than a week after the club organized an exclusive pop-up vaccine clinic that was later cancelled.

In an email sent last night to club members, board president Carol Fraser stated it had been a “very busy week” for Hollyburn’s board and management team. “We wanted to let you know that on April 28, six Hollyburn board members tendered their resignations.”  

Members of the club have stood divided recently, after the club had been set to host Indigo Pharmacy on April 26 in order to offer “a very limited quantity of the first dose of the AstraZeneca vaccine for members ages 40 to 65,” according to an April 22 email sent to members by Hollyburn CEO Ed McLaughlin.

On April 23, the province officially cancelled the club’s pop-up clinic, labelling it “unacceptable.”

“We cancelled the clinic and won’t be providing any further COVID-19 vaccines to this pharmacy,” a health ministry spokesperson said in an emailed response to the North Shore News.

In an email sent to club members on April 26, Fraser clarified that the pop-clinic had initially been organized in order to vaccinate Hollyburn staff and there was “no payment made to the pharmacist from Hollyburn for this.”

When it became clear that there would be 42 leftover vaccines, members in the appropriate age range were then offered appointments on a first-come, first-served basis. All 42 appointments were booked within six minutes and a wait list of 250 members was generated, according to the email.

“The distribution of vaccines in this manner has been called ‘elitist’ and ‘tone-deaf,’ given the current climate and clearly lacking in sensitivity to the broader issues around the distribution of COVID-19 vaccines and this became very apparent to us once the cancelled clinic garnered the attention of the media on Friday evening,” stated Fraser, in the April 26 email. “For this lack of sensitivity and judgment, we sincerely apologize.”

Earlier this week, two online petitions began circulating among club members. One petition, which has received more than 400 signatures, has called for the removal of McLaughlin in response to the planned clinic.

Another petition, which so far has received more than 1,000 signatures, was launched to counter the initial petition and has called for members to support McLaughlin as well as the club executive and board of directors.

Fraser confirmed that six members of Hollyburn’s 16-person board resigned on April 28, though she could not specify if their resignations were specifically due to the events of the past week.

“Hollyburn respects the rights of these board members to terminate their positions with the board, and the club remains grateful for the contributions these members made during their time on the board,” stated Fraser, in an emailed response to the North Shore News. “As a private club, and as you can appreciate, the specific dealings of the board are confidential, and matters discussed at the board must remain as such.”

 

Second story published April 26 at 11:25 a.m. with a brief update on April 27

West Vancouver country club members have mixed views after 'vaccination scandal' by Ben Bengtson and Elisia Seeber

Members of the Hollyburn Country Club stand divided after the club organized an exclusive pop-up vaccine clinic that was later cancelled.

While some angered members of the West Vancouver club are calling for a change of leadership and the “immediate removal” of chief executive Ed McLaughlin, others are in support of his efforts to keep everyone at the club safe.

The club was set to host Indigo Pharmacy on April 26, from noon to 3 p.m. to offer “a very limited quantity of the first dose of the AstraZeneca vaccine for members ages 40 to 65,” according to an April 22 email sent to members by McLaughlin.

The email stated there are long wait-lists for COVID-19 vaccines in local communities and members could book an appointment by providing their name, membership number and a preferred time slot.

B.C. residents have been told previously to book their AstraZeneca vaccine directly through local pharmacies.

The B.C. government later cancelled the club’s pop-up clinic, labelling it “unacceptable.”

“We cancelled the clinic and won’t be providing any further COVID-19 vaccines to this pharmacy,” a health ministry spokesperson said in an emailed response to the North Shore News.

Since news broke of the pop-up clinic, two change.org petitions have begun circulating.

One petition, 'Vaccination Scandal: Change the leadership at Hollyburn Country Club,' kicked off by club member Chris Browne over the weekend, received more than 180 signatures in less than 24 hours in support of McLaughlin's removal.

These members are outraged that their mission statement, ‘friends, family, community,’ has been “corrupted by the senior leadership of our club to mean selfish privilege” according the petition.

“We believe this project reflects an indefensible lack of judgment by the leadership of the club that demands appropriate repercussions,” Browne wrote on change.org, adding that the group is also calling for the resignation of any directors who were aware of and condoned this project.

In response to the group calling for McLaughlin to resign, a second petition, 'Please support HCC CEO, Ed McLaughlin, Club Executive & Board of Directors,' was started by members in support of the chief executive and board members, which received more than 800 signatures in a day.

“At times like this, we feel it is important to speak up and show our support of the HCC team that has worked tirelessly and transparently throughout this pandemic,” Carlota Lee and Dana Inman wrote on the petition.

In a statement on April 24, McLaughlin apologized for the club organizing a vaccine clinic, not available to the general public, without further consideration.

He said the club consulted with the pharmacy that delivers staff's yearly flu vaccinations, to schedule the vaccination clinic for staff who are eligible for the AstraZeneca vaccine (aged 40 and over) and there were more vaccines than needed. 

“When there were more vaccines available than staff who were eligible and who chose to participate, the decision was made to offer the remaining vaccines to eligible members who had not yet received their first vaccine,” McLaughlin said in the statement.

He said Hollyburn offered no compensation to the pharmacist and no vaccines would have been offered to members if the available vaccines had been fully used by staff.

“While our intention was to do our utmost to protect the health and safety of our community, we cancelled the program in response to guidance from the health authority,” McLaughlin said.

“Given the current environment in which everyone is anxious to receive a vaccine, we understand the concern that has been expressed about offering a clinic that is not available to the general public. We apologize for having organized the clinic without full consideration of this.”

Browne said the decision to host the clinic demonstrated “an unacceptable level of insensitivity” and was “irresponsible and unacceptable.”

“There is simply no justification for Hollyburn members or staff to jump the queue ahead of any other Canadian and it is even more reprehensible, given the much more severe outbreak in the Fraser Health Authority, that vaccination spots be taken away from communities or individuals in need.”

While supporters, Lee and Inman, “believe that all decisions were made with the best intentions to support the HCC employees.”

West Vancouver Mayor Mary-Ann Booth was not in support.  After being members for 25 years, Booth announced Saturday (April 24) she and her family would be cancelling their Hollyburn memberships in response to news of the proposed pop-up clinic.

Booth said neither she nor her husband had seen the email by the country club informing members of the vaccine clinic when it was sent out a few days ago. She said she was "appalled" to learn about the plan from reports in the media.

"I couldn't believe it, actually. ... It looked like people were jumping the queue and getting special treatment. I don't believe in that," said Booth. "I cancelled my membership at 12:20 today."

The mayor has been quarantining at home after her husband contracted COVID-19.

“Given what I have come through with my husband and being in quarantine until tomorrow, I do encourage everybody to get registered and get vaccinated as soon as they can – and follow the proper channels and publicly approved process," she said.

Earlier this week, the province started offering the AstraZeneca vaccine to people 40 and over.

On Thursday, provincial Health Minister Adrian Dix said he expects the province’s supply of AstraZeneca vaccine to be depleted in the coming week.

 

Original story first published April 24 at 10:03 a.m.

Province Nixes Planned 'Pop-up' Vaccine Clinic at West Van's Hollyburn Country Club by Ben Bengtson

A planned “pop-up” vaccine clinic that would have been offered at Hollyburn Country Club next week has been cancelled by the B.C. government.

The West Vancouver country club was set to host Indigo Pharmacy on Monday, April 26 from noon to 3 p.m. to offer “a very limited quantity of the first dose of the AstraZeneca vaccine for members ages 40 to 65,” according to an April 22 email sent to members by Hollyburn CEO Ed McLaughlin.

The email stated there are long wait-lists for COVID-19 vaccines in local communities and members could book an appointment by providing their name, membership number and a preferred time slot.

Indigo Pharmacy has branches in Vancouver and New Westminster, according to its website.

B.C. residents have been told previously to book their AstraZeneca vaccine directly through local pharmacies.

In a statement to the North Shore News, the province said the pop-up clinic had been cancelled.

“This is unacceptable. We cancelled the clinic and won’t be providing any further COVID-19 vaccines to this pharmacy,” the statement read.

After being members for 25 years, West Vancouver Mayor Mary-Ann Booth announced Saturday (April 24) she and her family would be cancelling their Hollyburn memberships in response to news of the proposed pop-up clinic.

Booth said neither her or her husband had seen the email by the country club informing members of the vaccine clinic when it was sent out a few days ago. She said she was "appalled" to learn about the plan from reports in the media.

"I couldn't believe it, actually. ... It looked like people were jumping the queue and getting special treatment. I don't believe in that," said Booth. "I cancelled my membership at 12:20 today."

The mayor has been quarantining at home after her husband contracted COVID-19.

“Given what I have come through with my husband and being in quarantine until tomorrow, I do encourage everybody to get registered and get vaccinated as soon as they can – and follow the proper channels and publicly approved process," she said.

Earlier this week, the province started offering the AstraZeneca vaccine to people 40 and over.

On Thursday, provincial Health Minister Adrian Dix said he expects the province’s supply of AstraZeneca vaccine to be depleted in the coming week. 

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6 Hollyburn Country Club board members resign, less than a week after 'vaccination scandal' - North Shore News
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Pop-up vaccine clinics: Hopefuls turned away as Fraser Health ends mobile sites - CTV News Vancouver

VANCOUVER -- Rumours that Guildford Recreation Centre had available vaccines in a pop-up clinic had hopefuls rushing to get their dose, but Fraser Health says they are only vaccinating people who are eligible and booked in advance.

The confusion comes in the wake of a series of short-term vaccination clinics in COVID-19 hotspots that were cancelled after just three days in the wake of a public backlash. Word of the pop-up clinics spread almost exclusively through text messages and hundreds of people spent hours in line only to be sent home unvaccinated when supplies ran out.

While the pop-ups have ended, the rumours continue and dozens have been attending the site looking for a shot.

"Fraser Health does not have any further pop-up or drop-in COVID-19 immunization clinics planned in our region at this time," wrote a spokesperson on Friday. "The Guildford Recreation Centre is an existing COVID-19 immunization site for eligible people with booked appointments. It is not providing immunizations to people who do not have booked appointments."

However, staff at the site are registering people and notifying them of any availability later in the day or at a later time via text message.

"If there is no capacity available, staff will assist people in booking an appointment for them at a neighbouring immunization clinic that has appointments available," wrote the spokesperson. "Those who live in high-transmission neighbourhoods, and other eligible people, are encouraged to register for immunization right away on the Get Vaccinated website so they can book their appointments and to get immunized."

The age-based rollout has expanded to those in their 50s, who are now eligible for the Pfizer vaccine and are encouraged to register on the provincial website to more easily make an appointment. The health minister says those in their 40s should be eligible next week. 

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Pop-up vaccine clinics: Hopefuls turned away as Fraser Health ends mobile sites - CTV News Vancouver
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Pfizer to export U.S.-made COVID-19 shots to Canada starting next week - CTV News

OTTAWA -- Pfizer Inc will next week start supplying Canada with COVID-19 vaccine made in its U.S. plant, a senior official said on Friday, making it the second country to receive doses from the Kalamazoo, Mich. facility.

Reuters reported on Thursday that Pfizer had started shipping vaccines made at the plant to Mexico, the first time it has delivered abroad from U.S. facilities after a Trump-era restriction on dose exports expired at the end of March.

"I can confirm that as of May 3, the Canadian supply of the Pfizer/BioNTech vaccine will come from its manufacturing site in Kalamazoo," said federal Procurement Minister Anita Anand.

"We expect to remain on the same delivery schedule, with 2 million doses expected each week in May, starting next week, and 2.4 million doses each week in June," she told a briefing.

Canada has deals with Pfizer for up to 76 million doses. Previous Canadian shipments from Pfizer and German partner BioNTech SE had come from Pfizer's main European plant in Belgium.

(Reporting by David Ljunggren; Editing by Cynthia Osterman)

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Pfizer to export U.S.-made COVID-19 shots to Canada starting next week - CTV News
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Anxiety caused COVID-19 vaccine reactions in 5 U.S. states, health officials say - CBC.ca

Anxiety — not a problem with the shots — that caused reactions in dozens of people at coronavirus vaccine clinics in five states, U.S. health officials have concluded.

Experts say the clusters detailed Friday by the Centers for Disease Control and Prevention are an example of a phenomenon that's been chronicled for decades about a variety of different vaccines. Basically, some people get so freaked out by injections that their anxiety spurs a physical reaction.

"We knew we were going to see this" as mass COVID-19 vaccine clinics were set up around the world, said Dr. Noni MacDonald, a Canadian researcher who has studied similar incidents.

The CDC authors said the reports came in from  April 7 to 9 and involved clinics in California, Colorado, Georgia, Iowa and North Carolina. The investigation was based on interviews with, and reports by, clinic staff.

Many of the 64 people affected either fainted or reported dizziness. Some got nauseous or vomited, and a few had racing hearts, chest pain or other symptoms. None got seriously ill.

All received the Johnson & Johnson vaccine. Four of the the five clinics temporarily shut down as officials tried to sort out what was happening. Health officials at the time said they had no reason to suspect a problem with the vaccine itself.

1-dose vaccine

Of the three COVID-19 vaccines authorized in the U.S., only J&J's can be administered in just one dose. That probably makes it more appealing to people who are nervous about shots and might leave them "more highly predisposed to anxiety-related events," the CDC report said.

Some of the sites advertised they were giving J&J shots, noted Dr. Tom Shimabukuro, who leads the CDC's COVID-19 vaccine safety monitoring work and is one of the study's authors.

The CDC found that about a quarter of the people reporting side-effects had similar things happen following past vaccinations.

WATCH | Specialist on why Johnson & Johnson's COVID-19 vaccine is 'fantastic':

The Johnson & Johnson COVID-19 shot is a 'fantastic' vaccine with benefits that outweigh the risks, says Dr. Isaac Bogoch, an infectious diseases specialist in Toronto. 2:39

The post-shot reactions differ from a very rare kind of side-effect that led to a pause in administration of the J&J vaccine. At least 17 vaccine recipients have developed an uncommon kind of blood clot that developed in unusual places, such as veins that drain blood from the brain, along with abnormally low levels of the platelets that form clots.

Other types of side-effects from the coronavirus vaccines are not unusual. Another CDC report released Friday looked at side-effects reported by more than 300,000 J&J vaccine recipients. More than half said they experienced a sore arm, fatigue or headache. A third reported fever or chills, and about a fifth said they were nauseous.

But the clusters at the five clinics are believed to be stress-related.

Chain reaction

MacDonald, a professor of pediatrics at Dalhousie University in Nova Scotia, said studies have indicated that 10 per cent to 15 per cent of adults are afraid of injections.

Many people who experience stress-related symptoms are younger, and past clusters from other shots have involved school students. Some hyperventilate, some experience nausea, some reported headaches. And some had what at first appears to be more severe, neurological symptoms, she said.

One cluster that MacDonald reviewed involved 14 U.S. military reservists who developed symptoms after getting flu shots in 2009. The first was a 23-year-old man who one day later reported progressive weakness in his arms and legs but fully recovered.

"Everybody thinks this is [only] young teenage girls" who experience this, MacDonald said. "Well, it isn't."

It can start with one person fainting that can set off a chain reaction of symptoms in anxious people who see or hear about that first person. These days, people also react to things they read or watch in Facebook posts or on other sites.

Some doctors have referred to the phenomenon as a form of mass hysteria, but MacDonald rejected the term.

"These people are not crazy," but rather are experiencing real physical responses to psychological stress, she said.

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Anxiety caused COVID-19 vaccine reactions in 5 U.S. states, health officials say - CBC.ca
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One dose of Pfizer's COVID-19 vaccine still leaves recipients vulnerable to variants: U.K. study - The Globe and Mail

Inside Salisbury Cathedral in Salisbury, England, in January, healthcare workers get ready to inject residents with the Pfizer-BioNTech vaccine.

Frank Augstein/The Associated Press

Researchers in Britain have found that one dose of the Pfizer-BioNTech vaccine provides insufficient protection against new variants of the COVID-19 virus and urged public health officials to be vigilant about ensuring that people receive a second injection.

“We’re looking rather vulnerable to variants after one dose,” said Danny Altmann, a professor of immunology at Imperial College London who co-authored the research.

Dr. Altmann said the findings were especially relevant to countries such as Britain, where most people have had only one dose of a vaccine so far. More than 34.2 million people in the United Kingdom have had one shot and 14.5 million have had two.

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“For the situation of countries like the U.K., we’re saying hang on a minute, those people are doing well at the moment, and the U.K. has done well, but watch out and keep your eye on the ball for the variants because [people] are far more vulnerable than you might have expected to the variant strains,” he told a media briefing on Friday.

AstraZeneca, Moderna, Pfizer or Johnson & Johnson: Which COVID-19 vaccine will I get in Canada?

In a study released Friday, the scientists tracked 731 British health care workers for several months last year. About half of those in the study group had contracted COVID-19 during the first wave of the pandemic in March, 2020, while the remainder had not been infected.

The study found that those who’d previously had a mild or even asymptomatic infection had a far higher immune response after one dose of the Pfizer vaccine than those who hadn’t been ill. The immune response was so strong, the study said, that it also offered good protection against the variants first detected in Britain and South Africa.

The study “is basically showing that if you’ve had prior COVID-19, and then you’ve had a single dose vaccine, you are really in a different league in terms of your immune response,” said Rosemary Boyton, a professor of immunology and respiratory medicine at Imperial College who co-authored the study. “It’s almost like the infection has acted as a prime and the first dose has acted as a boost.”

However, the group of volunteers who had not been infected showed a much weaker immune response to the variants after one dose. The study showed that their level of neutralizing antibodies was 11- to 25-fold lower against the B. 1.1.7 variant compared with the original version of the virus, “resulting in the majority of individuals falling below the protective threshold.”

The research team said their findings also likely apply to other variants in circulation, such as the P.1, first detected and Brazil, and the B.1.617 and B.1.618 variants, first associated with India.

While the U.K. has seen a dramatic drop in infections, deaths and hospitalizations since January, when a variant detected outside London began to spread rapidly, Dr. Altmann urged caution given that new mutations have surfaced.

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“One dose in terms of all of our measurable immune parameters of [the Pfizer vaccine] really does look very, very feeble and all the more so against variants,” he said. “And yet whatever the level of immunity that it’s induced, it’s certainly been enough to have had some impact. But it’s really very, very weak compared to two doses. My message from that would be hang on in there for your second dose.”

Both researchers stressed that they weren’t suggesting that vaccines won’t work, but that the public should be careful about the level of protection one jab offers.

“All I would say loud and clear is we’re definitely not saying that the vaccines are useless,” Dr. Altmann said. “We’re actually saying the vaccines are incredibly good. But what we are saying for a country for example like the U.K. that has the majority of its vaccinated people on one dose and also has one eye on the horizon for any incoming variants of concern, that’s a potential real vulnerability. And a solution would be to keep up your guard on the surveillance of variants and get the second dose to people.”

Britain reported 2,381 infections on Friday and 15 deaths as the pandemic continued to show signs of easing. By contrast, the daily infection total in January was frequently above 60,000, and more than 1,200 deaths were announced each day.

Figures released Friday from Public Health England also showed that more than half of the U.K.’s population – 34.5 million people – live in parts of the country that have gone two weeks without a single death from the virus.

“We have come a long way since the beginning of the year, when we saw 20 times the level of infection we see now,” said Sarah Crofts, who runs a weekly infection survey at the Office for National Statistics. “The infection rate has continued to decrease across the U.K., and we are back to levels seen near the end of last summer.”

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Health columnist André Picard answers reader questions about COVID-19 variants, how effective the various vaccines are and the impact of on-again, off-again lockdowns. The Globe and Mail


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In past years, Kulpreet Singh’s neighbourhood group chats online have been filled with political discussion and questions about lost cats.

These days, however, phone app WhatsApp – a messaging platform – are full of inquiries the Lower Mainland resident never thought he would see.

“In my neighbourhood group, someone posted this morning, asking, does anyone know if there are any vaccination pop ups today?” Singh, the founder of the South Asian Mental Health Alliance, told Black Press Media by phone Thursday (April 29), just hours after Fraser Health suspended its much-maligned system of pop-up clinics.

“I would never imagine someone would be asking where to get vaccinated in my local neighbourhood group,” he said, adding that ideally, these details would be listed on the health authority website, with dates and the requirements, as well as a registration process and updates on daily spaces.

SFU professor Valorie Crooks agrees. The creator of the COVID-19 Risks in British Columbia’s Neighbourhoods project said that the “whisper network,” or informal spaces being used to share information, wasn’t working.

While vaccines were brought to high-risk neighbourhoods, Crooks said, what remained lacking was transparency.

The whole idea of a pop-up clinic may be flawed from the get-go. Pop-up shops, she noted, do rely on the idea of surprise and scarcity, but that might not be the route British Columbians want health officials to go.

Fraser Health ran 10 pop-up vaccine clinics, beginning April 24. At least four – Cloverdale, Surrey North, South Langley Township and Port Coquitlam – were announced only after they had already began, with many people standing in line for hours.

Fraser Health said 6,000 people were vaccinated, but apologized for their lack of communication about the clinics.

“People want to get a better understanding of how do we actually choose these sites? And also, how are we informing people about the availability of this,” Crooks said.

However, she sympathized with an attempt by Fraser Health to do what many had been asking; go into high-risk neighbourhoods directly.

“I think that having are doubling down on the idea of bringing vaccines into communities where the rates are high, or risks are high, is a positive thing,” Crooks said. “This is something that many public health experts across Canada and internationally have said is an effective strategy.”

But even as Fraser Health tried to push down some barriers to vaccination, Crooks said they created others by not spreading the word in a way that allowed all people, including vulnerable frontline workers, to access immunizations.

Singh said that the pop-ups likely damaged confidence in the vaccine rollout altogether.

“What I heard on site was an individual in my network, who went on-site at around 7:40 a.m. in the morning, he waited six hours to get his vaccination,” Singh said, noting that this person, like many others, received conflicting information about the number of doses available and who would get one.

Singh is glad that Fraser Health suspended their pop-up clinics to look for more equitable solutions. While both the health ministry and Fraser Health have said they’ve been in contact with the BIPOC (Black, Indigenous and people of colour) communities in hot spot zones, Singh said that bureaucracy has often gotten in the way of that.

READ MORE: Fraser Health apologizes for confusion, says no more COVID vaccine pop-up clinics planned

While there is little to no AstraZeneca in B.C. right now, health officials have said they will rethink the program when supply returns. Singh hopes that will involve using mobile clinics, similar to a program in Surrey, or family doctors to get the word out to their patients.

But Singh cautioned against making volunteers shoulder the burden of vaccine education and access like Toronto has done with the Vaccine Hunters Twitter account.

“Those groups, vaccine hunters, they’re putting labor to help and support people’s health and well being, whereas large systems already exist of people who are being paid to do these jobs.”

The rumours and lack of concrete information, Singh said, has only amplified the feelings of trauma and exhaustion already felt by many in the South Asian community.

“I’m concerned right now about frontline and essential workers, and especially new immigrants and international students who are going through different waves of trauma because of their family situation and home situation in India, with the second wave of COVID, and the farmer protests,” he said.

“Then on top of that working frontline, during the pandemic here in Canada, and then them not even able to get a vaccine in an equitable way is not really fair. The least we could do to respect them and the sacrifices that they’re making working on the front line is to make sure that they get the vaccine.”


@katslepian

katya.slepian@bpdigital.ca

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Lack of clear vaccine info from B.C. officials leading to rumours, distrust: advocates - Peninsula News Review
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COVID-19 update for April 30: B.C. government to release details of enforcement on travel ban | 853 new cases, record ICU cases - Vancouver Sun

Here's your daily update with everything you need to know on the novel coronavirus situation in B.C.

Article content

Here’s your daily update with everything you need to know on the novel coronavirus situation in B.C. for April 30, 2021.

We’ll provide summaries of what’s going on in B.C. right here so you can get the latest news at a glance. This page will be updated regularly throughout the day, with developments added as they happen.

Check back here for more updates throughout the day. You can also get the latest COVID-19 news delivered to your inbox weeknights at 7 p.m. by subscribing to our newsletter here.


B.C.’S COVID-19 CASE NUMBERS

As of the latest figures given on April 29:

• Total number of confirmed cases: 128,742 (7,996 active cases)
• New cases since April 26: 853
• Total deaths: 1,577 (1 new death)
• Hospitalized cases: 503
• Intensive care: 178
• Total vaccinations: 1,749,375 doses administered (90,296 second doses)
• Cases under public health monitoring: 11,628
• Recovered: 118,937
• Long-term care and assisted-living homes, and acute care facilities currently affected: 12

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IN-DEPTH:COVID-19: Here are all the B.C. cases of the novel coronavirus


B.C. GUIDES AND LINKS

COVID-19: Here’s everything you need to know about the novel coronavirus

COVID-19 FAQ: What you need to know about the vaccine rollout in B.C.

COVID-19: Have you been exposed? Here are all B.C. public health alerts

COVID-19 at B.C. schools: Here are the school district exposure alerts

COVID-19: Avoid these hand sanitizers that are recalled in Canada

COVID-19: Here’s where to get tested in Metro Vancouver

B.C. COVID-19 Symptom Self-Assessment Tool


LATEST NEWS ON COVID-19 IN B.C.

3 p.m. – Health officials are set to share latest figures on COVID-19 in B.C.

Health officials are expected to update the number of COVID-19 cases, deaths and recoveries across the province.

10 a.m. – Minister to release enforcement details of COVID-19 travel ban in B.C.

British Columbia’s solicitor general is expected to announce more details about enforcement of a travel ban aimed at reducing the spread of COVID-19.

Mike Farnworth, who is also the public safety minister, announced orders a week ago to limit non-essential travel between three regional zones until May 25.

He has said police will conduct periodic road checks at key travel points and violators could be issued $575 fines.

The National Police Federation has criticized the order, saying it lacks clarity and that its RCMP members in B.C. are at risk of public backlash and exposure to the virus due a slow immunization rollout for officers.

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The B.C. Civil Liberties Association has said Indigenous, Black and racialized communities could be at risk of negative harmful impacts when dealing with police.

However, Farnworth has maintained the province sought input from racialized communities.

-The Canadian Press

5 a.m. – Death due to B.C. COVID-19 parties could lead to manslaughter charges: experts

People who break health rules by holding parties that lead to death from COVID-19 should heed the warning from a British Columbia judge about facing a manslaughter charge, legal experts say.

Prof. Lisa Dufraimont of York University’s Osgoode Hall law school said manslaughter charges stem from an unlawful act that causes death and a foreseeable activity that could cause bodily harm.

“And if in fact it does cause someone’s death, as the judge said, then that could amount to manslaughter,” Dufraimont said in an interview Thursday.

“The judge is right about that.”

Provincial court Judge Ellen Gordon chastised Mohammad Movassaghi this week as she sentenced him to one day in jail, a $5,000 fine and 18 months’ probation. He had previously pleaded guilty to disobeying a court order, failing to comply with a health officer’s order and unlawfully purchasing grain alcohol.

The court heard he held a party for 78 people in a penthouse condominium that was about 165 square metres in size that police described as a makeshift nightclub.

-The Canadian Press

12 a.m.– 853 new cases, record ICU cases; vaccines on the way

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B.C. provincial health officer Dr. Bonnie Henry announced 853 new reported cases of COVID-19 on Thursday, bringing the total to date in the province to 128,742.

There are 178 people in intensive care with COVID-19, the highest to date.

There have been one additional death, nudging the death toll to 1,577.

Henry said B.C. is expecting to receive the single-dose Johnson & Johnson vaccine next week.

B.C. will also receive about one million doses of Pfizer next month, which Henry said will accelerate the age-based program.


B.C. VACCINE TRACKER



LOCAL RESOURCES for COVID-19 information

Here are a number of information and landing pages for COVID-19 from various health and government agencies.

B.C. COVID-19 Symptom Self-Assessment Tool

Vancouver Coastal Health – Information on Coronavirus Disease (COVID-19)

HealthLink B.C. – Coronavirus (COVID-19) information page

B.C. Centre for Disease Control – Novel coronavirus (COVID-19)

Government of Canada – Coronavirus disease (COVID-19): Outbreak update

World Health Organization – Coronavirus disease (COVID-19) outbreak

– With files from The Canadian Press

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COVID-19 update for April 30: B.C. government to release details of enforcement on travel ban | 853 new cases, record ICU cases - Vancouver Sun
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Quebecers 50 and over can now book coronavirus vaccine appointments - CTV News Montreal

MONTREAL -- Quebecers 50 years old and over can now book appointments for COVID-19 vaccines.

The morning after provincial health authorities announced vaccination appointments will begin to be opened for the general population in the coming weeks, the Clic Sante site is now accepting appointments for those over 50.

Quebec is expecting a large shipment of 2,517,080 vaccine doses over the next several weeks including 450,000 doses of the Pfizer vaccine, which are expected every week.

Director of public health Horacio Arruda said Thursday that more Moderna vaccines are also heading to Quebec, with 130,000 delivered Thursday and 230,000 doses coming the week of May 10.

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